Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 14/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22931783 | 1.00 | EPHX2 (0.41) | EPHX2FLT3DHODHMAPK14RET | |
| SCHEMBL29420794 | 0.89 | EPHX2 (0.44) | EPHX2FLT3RET | |
| SCHEMBL24754845 | 0.89 | EPHX2 (0.44) | EPHX2FLT3RET | |
| SCHEMBL29420788 | 0.87 | EPHX2 (0.43) | EPHX2FLT3 | |
| SCHEMBL22931804 | 0.87 | EPHX2 (0.43) | EPHX2FLT3MAPK14RET | |
| SCHEMBL24754812 | 0.87 | EPHX2 (0.43) | EPHX2FLT3 | |
| SCHEMBL29420791 | 0.87 | EPHX2 (0.43) | EPHX2FLT3MAPK14RET | |
| SCHEMBL24755078 | 0.82 | EPHX2 (0.42) | EPHX2DHODH | |
| SCHEMBL29420789 | 0.82 | EPHX2 (0.42) | EPHX2DHODH | |
| SCHEMBL22931769 | 0.80 | EPHX2 (0.52) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114174291-A | 1,2, 4-oxadiazol-5-one derivatives for the treatment of cancer | 巴斯利尔药物国际股份公司 | 2022-03-11 | — | — | CN | claimed |
| CN-114174291-A | 1,2, 4-oxadiazol-5-one derivatives for the treatment of cancer | 巴斯利尔药物国际股份公司 | 2022-03-11 | — | — | CN | disclosed |