Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 18/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MITF | O75030 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28718589 | 1.00 | ABL1 (0.64) | ABL1MEN1KMT2AMITFSMN1; SMN2 | |
| SCHEMBL15388513 | 0.82 | ABL1 (0.69) | ABL1 | |
| SCHEMBL29421212 | 0.82 | ABL1 (0.69) | ABL1 | |
| SCHEMBL19226034 | 0.82 | ABL1 (0.69) | ABL1 | |
| SCHEMBL15388285 | 0.82 | ABL1 (0.69) | ABL1 | |
| SCHEMBL20419224 | 0.82 | ABL1 (0.65) | ABL1 | |
| SCHEMBL28717834 | 0.80 | ABL1 (0.70) | ABL1 | |
| SCHEMBL28717837 | 0.80 | ABL1 (0.70) | ABL1 | |
| SCHEMBL29421257 | 0.80 | ABL1 (0.70) | ABL1 | |
| SCHEMBL15391636 | 0.80 | ABL1 (0.65) | ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149409-B | (hetero) aryl amide compound with protein kinase inhibition activity | 中国药科大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-115109048-B | (hetero) aryl amide compound | 中国药科大学 | 2023-12-08 | — | — | CN | disclosed |
| CN-115109048-A | (hetero) aryl amide compound | 中国药科大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-114149409-A | (hetero) aryl amide compound with protein kinase inhibitory activity | 中国药科大学 | 2022-03-08 | — | — | CN | disclosed |