Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 19/20 | 0.41 |
| ▸ | NTRK3 | Q16288 | 9/20 | 0.40 |
| ▸ | NTRK2 | Q16620 | 8/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29422688 | 0.92 | NTRK1 (0.39) | NTRK1NTRK3NTRK2JAK2PCSK9 | |
| SCHEMBL22688921 | 0.90 | NTRK1 (0.39) | NTRK1NTRK3NTRK2PCSK9 | |
| SCHEMBL22688850 | 0.85 | NTRK1 (0.47) | NTRK1NTRK3NTRK2 | |
| SCHEMBL22695336 | 0.85 | NTRK1 (0.47) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29422687 | 0.85 | NTRK1 (0.47) | NTRK1NTRK3NTRK2 | |
| SCHEMBL29422685 | 0.80 | NTRK1 (0.42) | NTRK1NTRK3NTRK2JAK2 | |
| SCHEMBL20359267 | 0.80 | NTRK1 (0.45) | NTRK1NTRK3NTRK2PCSK9 | |
| SCHEMBL20359268 | 0.80 | NTRK1 (0.45) | NTRK1NTRK3NTRK2PCSK9 | |
| SCHEMBL18376029 | 0.80 | NTRK1 (0.45) | NTRK1NTRK3NTRK2PCSK9 | |
| SCHEMBL22695324 | 0.79 | NTRK1 (0.40) | NTRK1NTRK3NTRK2JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974434-B1 | MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | ZHEJIANG HISUN PHARM CO LTD (CN) | 2025-11-19 | — | — | EP | disclosed |
| EP-3974434-A1 | MACROLIDE DERIVATIVES, PREPARATION METHOD AND APPLICATION THEREOF | Zhejiang Hisun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |