⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL507506 | 1.00 | — | — | |
| SCHEMBL28608823 | 1.00 | CYP1A2 (0.50) | — | |
| SCHEMBL29930921 | 1.00 | — | — | |
| SCHEMBL177799 | 1.00 | — | — | |
| SCHEMBL1193974 | 1.00 | — | — | |
| SCHEMBL29609775 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL4918177 | 0.98 | CYP1A2 (0.49) | — | |
| SCHEMBL28497926 | 0.98 | CYP1A2 (0.49) | — | |
| Hydrochloric Acid SCHEMBL28351893 | 0.98 | CYP1A2 (0.49) | — | |
| Alcohol SCHEMBL211787 | 0.92 | KCNA5 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118028259-A | Short-chain dehydrogenase and application thereof | 河北工业大学 | 2024-05-14 | — | — | CN | claimed |
| US-20250353836-A1 | N-(HYDROXYALKYL (HETERO)ARYL) TETRAHYDROFURAN CARBOXAMIDES AS MODULATORS OF SODIUM CHANNELS | VERTEX PHARMA (US) | 2025-11-20 | — | — | US | disclosed |
| US-20250275952-A1 | 4-METHYLSULFONYL-SUBSTITUTED PIPERIDINE UREA COMPOUNDS | MYOKARDIA INC (US) | 2025-09-04 | — | — | US | disclosed |
| EP-4568965-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| CN-119219631-B | BET protein bromodomain BD1 selective covalent inhibitor and preparation method and application thereof | 山东大学 | 2025-04-18 | — | — | CN | disclosed |
| US-12258333-B2 | N-(hydroxyalkyl (hetero)aryl) tetrahydrofuran carboxamides as modulators of sodium channels | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2025-03-25 | — | — | US | disclosed |
| CN-113710668-B | Condensed azines for EP300 or CBP modulation and indications thereof | OPNA生物公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-119219631-A | BET protein bromodomain BD1 selective covalent inhibitor and preparation method and application thereof | 山东大学 | 2024-12-31 | — | — | CN | disclosed |
| CN-118475580-A | Platelet-derived growth factor receptor (PDGFR) alpha inhibitors and uses thereof | 普罗根托斯治疗公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118028259-A | Short-chain dehydrogenase and application thereof | 河北工业大学 | 2024-05-14 | — | — | CN | disclosed |
| CN-117897384-A | CDK2 inhibitors | 缆图药品公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2024033454-A1 | HETEROARYL COMPOUNDS FOR THE TREATMENT OF CANCER | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |
| CN-115884977-A | Stereoselective preparation of selected purine phosphoramidates | 阿堤亚制药公司 | 2023-03-31 | — | — | CN | disclosed |
| US-20220117955-A1 | 4-METHYLSULFONYL-SUBSTITUTED PIPERIDINE UREA COMPOUNDS | MyoKardia, Inc. | 2022-04-21 | — | — | US | disclosed |
| EP-3953351-A1 | CONDENSED AZINES FOR EP300 OR CBP MODULATION AND INDICATIONS THEREFOR | Plexxikon Inc. (US) | 2022-02-16 | — | — | EP | disclosed |