Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 6/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 5/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1027918 | 0.98 | CYP3A4 (0.52) | CYP3A4L3MBTL1LPAR3LPAR2LPAR1 | |
| SCHEMBL10356563 | 0.85 | LPAR3 (0.60) | LPAR3LPAR2LPAR1 | |
| SCHEMBL2942277 | 0.85 | LPAR3 (0.60) | LPAR3LPAR2LPAR1 | |
| Zinc Ion SCHEMBL10354293 | 0.83 | AKT1 (0.37) | CYP3A4LPAR3LPAR2LPAR1LMNA | |
| SCHEMBL21553542 | 0.83 | SAT1 (0.45) | LPAR3LPAR2LPAR1 | |
| SCHEMBL6853819 | 0.83 | CYP3A4 (0.46) | CYP3A4L3MBTL1TSHRALDH1A1 | |
| SCHEMBL11428437 | 0.82 | LPAR3 (0.42) | CYP3A4LPAR3LPAR2LPAR1 | |
| SCHEMBL21440333 | 0.82 | CYP3A4 (0.53) | CYP3A4L3MBTL1LPAR3LPAR2LPAR1 | |
| SCHEMBL28355404 | 0.82 | AKT1 (0.46) | LPAR3LPAR2LPAR1ALDH1A1LMNA | |
| SCHEMBL28359503 | 0.82 | LPAR3 (0.43) | LPAR3LPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2010111622-A | PORE-SHRINKING AGENT | KAO CORP | 2010-05-20 | — | — | JP | disclosed |