Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.41 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | TDP2 | O95551 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29423919 | 1.00 | FFAR1 (0.41) | FFAR1LPLLIPGPPARGPPARD | |
| SCHEMBL16846002 | 1.00 | FFAR1 (0.41) | FFAR1LPLLIPGPPARGPPARD | |
| SCHEMBL18940305 | 0.89 | FFAR1 (0.44) | FFAR1LPLLIPGTDP2POLB | |
| SCHEMBL18940280 | 0.89 | FFAR1 (0.44) | FFAR1LPLLIPGTDP2POLB | |
| SCHEMBL15471370 | 0.88 | FFAR1 (0.48) | FFAR1LPLLIPGTDP2POLB | |
| SCHEMBL18346431 | 0.88 | FFAR1 (0.48) | FFAR1LPLLIPGTDP2POLB | |
| SCHEMBL15471521 | 0.88 | FFAR1 (0.48) | FFAR1LPLLIPGTDP2POLB | |
| SCHEMBL16845952 | 0.86 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL29423898 | 0.86 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL29423910 | 0.86 | FFAR1 (0.38) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |