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SCHEMBL29424527

SCHEMBL29424527

CC(C)(C)[Si](OCCN1CCN(CC[C@H](CSc2ccccc2)Nc2ccc(S(N)(=O)=O)cc2S(=O)(=O)C(F)(F)F)CC1)(c1ccccc1)c1ccccc1

nearest known ligand 0.72

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ BCL2L1 Q07817 19/20 0.72
▸ BCL2 P10415 15/20 0.46
▸ BAD Q92934 3/20 0.45
▸ BCL2L11 O43521 1/20 0.44
▸ CYP2C9 P11712 1/20 0.44
▸ MCL1 Q07820 1/20 0.44
▸ ASPH Q12797 1/20 0.44
▸ BCL2L2 Q92843 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL554040 1.00 BCL2L1 (0.72) BCL2L1BCL2BADBCL2L11CYP2C9
SCHEMBL554039 1.00 BCL2L1 (0.72) BCL2L1BCL2BADBCL2L11CYP2C9
SCHEMBL554106 0.91 BCL2L1 (0.59) BCL2L1BCL2BADBCL2L11CYP2C9
SCHEMBL554105 0.91 BCL2L1 (0.59) BCL2L1BCL2BADBCL2L11CYP2C9
SCHEMBL29424532 0.91 BCL2L1 (0.59) BCL2L1BCL2BADBCL2L11CYP2C9
SCHEMBL554895 0.88 BCL2L1 (0.67) BCL2L1BCL2BADBCL2L11CYP2C9
SCHEMBL555011 0.88 BCL2L1 (0.67) BCL2L1BCL2BADBCL2L11CYP2C9
SCHEMBL554894 0.88 BCL2L1 (0.67) BCL2L1BCL2BADBCL2L11CYP2C9
SCHEMBL29424528 0.87 BCL2L1 (0.68) BCL2L1BCL2BAD
SCHEMBL554649 0.87 BCL2L1 (0.68) BCL2L1BCL2BAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4556469-A1 BENZAMIDE COMPOUNDS Recurium IP Holdings, LLC (US) 2025-05-21 — — EP disclosed
EP-3972601-A1 NANOPARTICLE FORMULATION OF BCL-2 INHIBITOR Recurium IP Holdings, LLC (US) 2022-03-30 — — EP disclosed
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