SCHEMBL29424536

SCHEMBL29424536

NS(=O)(=O)c1ccc(N[C@H](CCN2CCC(O)C2)CSc2ccccc2)c(S(=O)(=O)C(F)(F)F)c1

nearest known ligand 0.77

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ BCL2L1 Q07817 12/20 0.77
▸ BCL2 P10415 17/20 0.51
▸ BAD Q92934 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22581194 1.00 BCL2L1 (0.77) BCL2L1BCL2BAD
SCHEMBL22581196 1.00 BCL2L1 (0.77) BCL2L1BCL2BAD
SCHEMBL29403793 0.96 BCL2L1 (0.80) BCL2L1BCL2BAD
SCHEMBL22581251 0.96 BCL2L1 (0.80) BCL2L1BCL2BAD
SCHEMBL22581252 0.96 BCL2L1 (0.80) BCL2L1BCL2BAD
SCHEMBL22581277 0.94 BCL2L1 (0.80) BCL2L1BCL2BAD
SCHEMBL22581276 0.94 BCL2L1 (0.80) BCL2L1BCL2BAD
SCHEMBL29424502 0.94 BCL2L1 (0.80) BCL2L1BCL2BAD
SCHEMBL15892239 0.90 BCL2L1 (0.78) BCL2L1BCL2BAD
SCHEMBL22879236 0.89 BCL2L1 (0.61) BCL2L1BCL2BAD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118084904-A Benzamide compounds 里科瑞尔姆IP控股有限责任公司 2024-05-28 — — CN disclosed
CN-111801327-B Benzamide compounds 里科瑞尔姆IP控股有限责任公司 2024-02-09 — — CN disclosed
EP-3972601-A1 NANOPARTICLE FORMULATION OF BCL-2 INHIBITOR Recurium IP Holdings, LLC (US) 2022-03-30 — — EP disclosed
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