Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29424743 | 0.95 | EPHX1 (0.48) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL5104597 | 0.83 | EPHX1 (0.47) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL28977448 | 0.83 | EPHX1 (0.47) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4623508 | 0.83 | EPHX1 (0.47) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL6629578 | 0.81 | EPHX1 (0.49) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL1128495 | 0.81 | EPHX1 (0.49) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL4342921 | 0.81 | EPHX1 (0.68) | EPHX1HPGDSMN1; SMN2NPC1GAA | |
| SCHEMBL28212010 | 0.80 | EPHX1 (0.44) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL29424741 | 0.79 | EPHX1 (0.43) | EPHX1HSD17B10HPGDSMN1; SMN2NPC1 | |
| SCHEMBL1319725 | 0.79 | EPHX1 (0.47) | EPHX1HSD17B10HPGDBTKSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107949558-B | Muscarinic agonists | 赫普泰雅治疗有限公司 | 2022-03-15 | — | — | CN | disclosed |