Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22533603 | 1.00 | BRD4 (0.47) | BRD4POLBMAPTTNFSMN1; SMN2 | |
| SCHEMBL29424847 | 0.92 | FGFR1 (0.47) | BRD4POLBMAPTTNFSMN1; SMN2 | |
| SCHEMBL22533573 | 0.92 | FGFR1 (0.47) | BRD4POLBMAPTTNFSMN1; SMN2 | |
| SCHEMBL22533669 | 0.87 | TNF (0.48) | BRD4TNFLMNAMAPK1FGFR1 | |
| SCHEMBL29424719 | 0.87 | TNF (0.48) | BRD4TNFLMNAMAPK1FGFR1 | |
| SCHEMBL22533978 | 0.85 | BRD4 (0.48) | BRD4POLBMAPTTNFSMN1; SMN2 | |
| SCHEMBL29424894 | 0.85 | BRD4 (0.48) | BRD4POLBMAPTTNFSMN1; SMN2 | |
| SCHEMBL22533663 | 0.85 | BRD4 (0.57) | BRD4POLBMAPTSMN1; SMN2LMNA | |
| SCHEMBL29424736 | 0.85 | BRD4 (0.57) | BRD4POLBMAPTSMN1; SMN2LMNA | |
| SCHEMBL27442466 | 0.80 | TNF (0.47) | BRD4TNFLMNAMAPK1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114040915-A | Bicyclic heteroaryl derivatives as ectonucleotide pyrophosphatase phosphodiesterase 1 inhibitors | 里伯赛恩斯有限责任公司 | 2022-02-11 | — | — | CN | disclosed |