SCHEMBL29425010

SCHEMBL29425010

CC(C)C[C@H](NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCCN)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 18/20 0.56
▸ NPY1R P25929 11/20 0.56
▸ NPY5R Q15761 8/20 0.56
▸ NPY2R P49146 7/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29666886 0.96 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29666900 0.96 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30531629 0.95 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29531807 0.95 NPY4R (0.60) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30490413 0.94 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30355277 0.94 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29385243 0.94 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30272464 0.93 NPY4R (0.55) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29872588 0.92 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29666908 0.92 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11628202-B2 Methods of reducing the need for surgery in patients suffering from benign prostatic hyperplasia NYMOX CORPORATION (CA) 2023-04-18 — — US claimed
US-12090191-B2 Method of enhancing the therapeutic efficacy of fexapotide triflutate in treating LUTS NYMOX CORPORATION (BS) 2024-09-17 — — US disclosed
US-20240252516-A1 COMBINATION BPH THERAPY WITH FEXAPOTIDE TRIFLUTATE, A 5-ARI, AND AN ALPHA BLOCKER NYMOX CORPORATION 2024-08-01 — — US disclosed
CN-110381984-B Compositions and methods for improving sexual function 尼莫克斯股份有限公司 2023-11-28 — — CN disclosed
US-20220226424-A1 METHOD OF ENHANCING THE THERAPEUTIC EFFICACY OF FEXAPOTIDE TRIFLUTATE IN TREATING LUTS NYMOX CORPORATION 2022-07-21 — — US disclosed
EP-4003387-A1 FOCAL TREATMENT OF PROSTATE CANCER Nymox Corporation (US) 2022-06-01 — — EP disclosed
EP-4003533-A1 METHODS OF TREATING MULTIFOCAL CANCER Nymox Corporation (US) 2022-06-01 — — EP disclosed
US-11298400-B2 Method of enhancing the therapeutic efficacy of fexapotide triflutate in treating LUTS NYMOX CORPORATION (BS) 2022-04-12 — — US disclosed
EP-3969112-A1 METHOD OF TREATING LOWER URINARY TRACT SYMPTOMS WITH FEXAPOTIDE TRIFLUTATE Nymox Corporation (US) 2022-03-23 — — EP disclosed
EP-3969030-A1 METHOD OF ENHANCING THE THERAPEUTIC EFFICACY OF FEXAPOTIDE TRIFLUTATE IN TREATING LUTS Nymox Corporation (US) 2022-03-23 — — EP disclosed
US-11278588-B2 Method of treating lower urinary tract symptoms with fexapotide triflutate NYMOX CORPORATION (BS) 2022-03-22 — — US disclosed
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