Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | PRKCB | P05771 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | STK3 | Q13188 | 1/20 | 0.45 |
| ▸ | MAP2K1 | Q02750 | 15/20 | 0.43 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224639 | 1.00 | AURKA (0.46) | AURKATNFRSF1AKDRMAP3K9KDM4C | |
| SCHEMBL23694115 | 0.94 | MAP2K1 (0.43) | AURKATNFRSF1AKDRMAP3K9KDM4C | |
| SCHEMBL30080297 | 0.94 | MAP2K1 (0.43) | AURKATNFRSF1AKDRMAP3K9KDM4C | |
| SCHEMBL38651248 | 0.88 | MAPT (0.44) | KDRKDM4CMAPT | |
| SCHEMBL31401592 | 0.88 | MAPT (0.44) | KDRKDM4CMAPT | |
| SCHEMBL27224635 | 0.88 | KDM4C (0.45) | AURKATNFRSF1AKDRMAP3K9KDM4C | |
| SCHEMBL30866578 | 0.88 | KDM4C (0.45) | AURKATNFRSF1AKDRMAP3K9KDM4C | |
| SCHEMBL31401828 | 0.86 | MAPT (0.43) | KDRKDM4CMAPT | |
| SCHEMBL23694114 | 0.86 | MAPT (0.43) | KDRKDM4CMAPT | |
| SCHEMBL31401761 | 0.85 | MAPT (0.41) | KDRKDM4CMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022018875-A1 | ARYLAMIDE DERIVATIVE-CONTAINING PHARMACEUTICAL COMPOSITION FOR TREATING OR PREVENTING CELL PROLIFERATION DISEASES | 中外製薬株式会社 | 2022-01-27 | — | — | WO | disclosed |