SCHEMBL29425939

C[C@H]1C(=O)C[C@@H]2C(C(=O)O)=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@@H]21

nearest known ligand 0.70

Predicted protein targets (top 4)

	gene	UniProt	supporting neighbours	confidence
▸	MAPT	P10636	2/20	0.70

▸	MEN1	O00255	1/20	0.61

▸	KMT2A	Q03164	1/20	0.61

▸	STAT3	P40763	15/20	0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30124791	0.90	MEN1 (0.73)	MAPTMEN1KMT2ASTAT3
SCHEMBL29425889	0.86	MAPT (0.68)	MAPTMEN1KMT2ASTAT3
SCHEMBL29426050	0.84	MAPT (0.74)	MAPTMEN1KMT2ASTAT3
SCHEMBL27898368	0.84	MAPT (0.74)	MAPTMEN1KMT2ASTAT3
SCHEMBL29425796	0.84	MAPT (0.74)	MAPTMEN1KMT2ASTAT3
SCHEMBL20572414	0.84	MAPT (0.74)	MAPTMEN1KMT2ASTAT3
Loganic Acid SCHEMBL29426077	0.82	MAPT (1.00)	MAPTMEN1KMT2ASTAT3
Loganic Acid SCHEMBL308008	0.82	MAPT (1.00)	MAPTMEN1KMT2ASTAT3
Loganic Acid SCHEMBL31179995	0.82	MAPT (1.00)	MAPTMEN1KMT2ASTAT3
SCHEMBL28003482	0.82	MAPT (0.53)	MAPTMEN1KMT2ASTAT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3409766-B1	AN ESTERASE THAT IS CAPABLE OF CONVERTING IRIDOIDS AND SECO-IRIDOIDS	N ZYME BIOTEC GMBH (DE)	2022-03-09	—	—	EP	disclosed