Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 8/20 | 0.35 |
| ▸ | MGLL | Q99685 | 2/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26631093 | 1.00 | CHRM4 (0.40) | CHRM4CHRM1CHRM2CHRM5CNR2 | |
| SCHEMBL26739514 | 1.00 | CHRM4 (0.40) | CHRM4CHRM1CHRM2CHRM5CNR2 | |
| SCHEMBL26631245 | 0.89 | CHRM4 (0.35) | CHRM4CHRM1CHRM2CHRM5MGLL | |
| SCHEMBL26739518 | 0.89 | CHRM4 (0.35) | CHRM4CHRM1CHRM2CHRM5MGLL | |
| SCHEMBL29426693 | 0.88 | CD274 (0.36) | CHRM4CHRM1CHRM2CHRM5MGLL | |
| SCHEMBL29426915 | 0.88 | CD274 (0.35) | CHRM4CHRM1CHRM2CHRM5MGLL | |
| SCHEMBL26739528 | 0.88 | CD274 (0.35) | CHRM4CHRM1CHRM2CHRM5MGLL | |
| SCHEMBL26631114 | 0.88 | CD274 (0.36) | CHRM4CHRM1CHRM2CHRM5MGLL | |
| SCHEMBL26631229 | 0.88 | CD274 (0.35) | CHRM4CHRM1CHRM2CHRM5MGLL | |
| SCHEMBL26739511 | 0.88 | CD274 (0.36) | CHRM4CHRM1CHRM2CHRM5MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4217062-B1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-09 | — | — | EP | claimed |
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | claimed |
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | claimed |
| WO-2022063784-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-31 | — | — | WO | claimed |
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |