SCHEMBL29427859

SCHEMBL29427859

CC(C)C[C@H](NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ERAP2 Q6P179 8/20 0.63
▸ ECE1 P42892 6/20 0.61
▸ IL1RN P18510 6/20 0.60
▸ ERAP1 Q9NZ08 5/20 0.60
▸ ACE P12821 2/20 0.57
▸ ANPEP P15144 1/20 0.57
▸ MMP2 P08253 1/20 0.53
▸ MMP9 P14780 1/20 0.53
▸ MMP8 P22894 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30500405 0.97 ECE1 (0.59) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL29516260 0.97 ERAP2 (0.61) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30506397 0.96 ERAP2 (0.59) ERAP2ECE1IL1RNERAP1ANPEP
SCHEMBL30436333 0.93 ECE1 (0.61) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30166489 0.93 ECE1 (0.61) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL30259624 0.93 ERAP2 (0.58) ERAP2ECE1IL1RNERAP1ACE
SCHEMBL11497997 0.93 ACE (0.60) ECE1ACE
SCHEMBL7046017 0.93 ACE (0.60) ECE1ACE
SCHEMBL7046020 0.93 ACE (0.60) ECE1ACE
SCHEMBL31256996 0.92 ERAP2 (0.62) ERAP2ECE1IL1RNERAP1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122050496-A Active ganoderic acid yield optimization method based on directed evolution cytochrome P450 上海交通大学 2026-05-15 — — CN disclosed
US-20250304985-A1 Genetically Engineered Plants for Increased Production of Vindoline NORTHEASTERN UNIVERSITY 2025-10-02 — — US disclosed
CN-119799834-A Method for directionally improving yield of active ganoderic acid based on modified membrane anchored cytochrome P450 上海交通大学 2025-04-11 — — CN disclosed
US-12252687-B2 Recombinant yeast and use thereof TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES (CN) 2025-03-18 — — US disclosed
CN-114958838-B High-strength saccharomyces cerevisiae artificial small promoters 中国科学院天津工业生物技术研究所 2025-02-28 — — CN disclosed
CN-116410283-B Application of plum PsERF B protein and coding gene thereof in regulating and controlling synthesis of plant anthocyanin 中国农业大学 2025-02-21 — — CN disclosed
CN-119307498-A Saccharomyces cerevisiae artificial promoter mutants 中国科学院天津工业生物技术研究所 2025-01-14 — — CN disclosed
CN-118185987-B Rice gene OsCWIN and application thereof 四川农业大学 2024-12-31 — — CN disclosed
CN-116926068-B Application of transcription mediator MED31 gene and interaction transcription factor thereof in improving fucoxanthin content in Phaeodactylum tricornutum 宁波大学 2024-06-28 — — CN disclosed
CN-118185987-A Rice gene OsCWIN and application thereof 四川农业大学 2024-06-14 — — CN disclosed
CN-116410283-A Application of plum PsERF1B protein and coding gene thereof in regulating and controlling synthesis of plant anthocyanin 中国农业大学 2023-07-11 — — CN disclosed
US-20220396759-A1 RECOMBINANT YEAST AND USE THEREOF TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES (CN) 2022-12-15 — — US disclosed
CN-114959919-A Method for constructing saccharomyces cerevisiae artificial small promoter library and application 中国科学院天津工业生物技术研究所 2022-08-30 — — CN disclosed
CN-114958838-A High-strength saccharomyces cerevisiae artificial small promoter 中国科学院天津工业生物技术研究所 2022-08-30 — — CN disclosed
US-11421199-B2 Recombinant yeast and use thereof TIANJIN INSTITUTE OF INDUSTRIAL BIOTECHNOLOGY, CHINESE ACADEMY OF SCIENCES (CN) 2022-08-23 — — US disclosed
CN-114907997-A Construction and application of diosgenin synthesis strain 中国科学院天津工业生物技术研究所 2022-08-16 — — CN disclosed
CN-111548401-B Salvia miltiorrhiza ERF-VII transcription factor SmERF73 and application thereof 中国中医科学院中药研究所 2022-08-02 — — CN disclosed
CN-111748022-B Curvularia lunata-derived steroid substance transport protein and coding gene and application thereof 中国科学院天津工业生物技术研究所 2022-05-31 — — CN disclosed
CN-113005139-B Application of transcription factor PsMYB1 in regulation and control of synthesis of peony petal anthocyanin 中国林业科学研究院林业研究所 2022-05-20 — — CN disclosed
CN-112852651-B Method for increasing yield of hydrocortisone produced by saccharomyces cerevisiae biotransformation 中国科学院天津工业生物技术研究所 2022-02-18 — — CN disclosed
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