Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.45 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | DRD5 | P21918 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23177723 | 1.00 | PTPN11 (0.46) | PTPN11DDB1CRBNL3MBTL1METAP1 | |
| SCHEMBL23789478 | 0.84 | DDB1 (0.49) | PTPN11DDB1CRBNL3MBTL1METAP1 | |
| SCHEMBL26674015 | 0.80 | PTPN11 (0.49) | PTPN11DDB1CRBNATRCA12 | |
| SCHEMBL25278585 | 0.80 | PTPN11 (0.45) | PTPN11DDB1CRBNL3MBTL1ATR | |
| SCHEMBL30759281 | 0.79 | PTPN11 (0.44) | PTPN11DDB1CRBNL3MBTL1METAP1 | |
| SCHEMBL27140539 | 0.77 | PTPN11 (0.45) | PTPN11DDB1CRBNL3MBTL1METAP1 | |
| SCHEMBL27140412 | 0.77 | PTPN11 (0.44) | PTPN11DDB1CRBNL3MBTL1KDM4E | |
| SCHEMBL30759274 | 0.76 | PTPN11 (0.47) | PTPN11DDB1CRBNL3MBTL1METAP1 | |
| SCHEMBL23177724 | 0.74 | CA1 (0.47) | L3MBTL1CA12CA1CA2CA9 | |
| SCHEMBL26673962 | 0.74 | PTPN11 (0.53) | PTPN11DDB1CRBNCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110511220-B | P-diaminobenzene derivatives as potassium channel modulators, process for their preparation and their use in medicine | 上海挚盟医药科技有限公司 | 2022-04-01 | — | — | CN | disclosed |