SCHEMBL29429574

CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@@H](N)Cc1c[nH]cn1)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](CO)C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](C(=O)N[C@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](CCC(=O)O)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CCCCN)C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCC(=O)O)C(=O)O)[C@H](C)O

nearest known ligand 0.69

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	GLP1R	P43220	17/20	0.69

▸	C5AR1	P21730	1/20	0.67

▸	NPY1R	P25929	1/20	0.67

▸	NPY2R	P49146	1/20	0.67

▸	NPY4R	P50391	1/20	0.67

▸	NPY5R	Q15761	1/20	0.67

▸	GCGR	P47871	4/20	0.64

▸	GIPR	P48546	1/20	0.64

▸	CCKBR	P32239	2/20	0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30403572	0.95	GLP1R (0.73)	GLP1RC5AR1NPY1RNPY2RNPY4R
SCHEMBL30116704	0.95	C5AR1 (0.71)	GLP1RC5AR1NPY1RNPY2RNPY4R
SCHEMBL30495687	0.94	NPY1R (0.68)	GLP1RC5AR1NPY1RNPY2RNPY4R
SCHEMBL31182679	0.93	GLP1R (0.72)	GLP1RNPY1RNPY2RNPY4RNPY5R
SCHEMBL29429581	0.92	NPY1R (0.74)	GLP1RC5AR1NPY1RNPY2RNPY4R
SCHEMBL29429583	0.92	NPY1R (0.74)	GLP1RC5AR1NPY1RNPY2RNPY4R
SCHEMBL30392169	0.92	C5AR1 (0.66)	GLP1RC5AR1NPY1RNPY2RNPY4R
SCHEMBL29965312	0.92	NPY1R (0.68)	GLP1RC5AR1NPY1RNPY2RNPY4R
SCHEMBL31402803	0.92	GLP1R (0.69)	GLP1RC5AR1NPY1RNPY2RNPY4R
SCHEMBL31182590	0.92	GLP1R (0.68)	GLP1RC5AR1NPY1RNPY2RNPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-108350046-B	Analogs of VDAC 1-derived peptides	在本-古里安大学的B．G．内盖夫科技与应用有限公司	2022-04-01	—	—	CN	disclosed