Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487651 | 1.00 | CA1 (0.54) | CA1MMP2CA14GAAHSD17B10 | |
| SCHEMBL19748760 | 1.00 | CA1 (0.54) | CA1MMP2CA14GAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL5230686 | 0.98 | CA1 (0.53) | CA1MMP2CA14GAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL5230683 | 0.98 | CA1 (0.53) | CA1MMP2CA14GAAHSD17B10 | |
| SCHEMBL8758371 | 0.81 | KDM4E (0.42) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL5328091 | 0.81 | CYP3A4 (0.53) | MMP2HSD17B10MEN1KMT2ALMNA | |
| SCHEMBL4431825 | 0.81 | NPSR1 (0.53) | MMP2GAAHSD17B10MEN1KMT2A | |
| SCHEMBL4431827 | 0.81 | NPSR1 (0.53) | MMP2GAAHSD17B10MEN1KMT2A | |
| SCHEMBL8758378 | 0.81 | KDM4E (0.42) | GAAMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL29588182 | 0.81 | NPSR1 (0.53) | MMP2GAAHSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3966226-A1 | MASP INHIBITORY COMPOUNDS AND USES THEREOF | Bayer Aktiengesellschaft (DE) | 2022-03-16 | — | — | EP | disclosed |