Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.53 |
| ▸ | KDM4A | O75164 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | GLS | O94925 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL825511 | 1.00 | KCNA5 (0.53) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL8018113 | 0.91 | KCNA5 (0.56) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL30159605 | 0.91 | KCNA5 (0.56) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL11346624 | 0.88 | KCNA5 (0.51) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL7258326 | 0.88 | KCNA5 (0.53) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL11520053 | 0.87 | KCNA5 (0.52) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL5841647 | 0.87 | KCNA5 (0.52) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL11520059 | 0.87 | KCNA5 (0.52) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL11346621 | 0.87 | KCNA5 (0.52) | KCNA5KDM4ACA12CA1CA7 | |
| SCHEMBL11354588 | 0.85 | KCNA5 (0.48) | KCNA5KDM4ACA12CA1CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3965891-A1 | ANTIBODY DRUG CONJUGATES | Takeda Pharmaceutical Company Limited (JP) | 2022-03-16 | — | — | EP | disclosed |
| CN-114173824-A | Antibody drug conjugates | 武田药品工业株式会社 | 2022-03-11 | — | — | CN | disclosed |