Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CLK2 | P49760 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TOP2A | P11388 | 5/20 | 0.53 |
| ▸ | TOP2B | Q02880 | 5/20 | 0.53 |
| ▸ | GSK3B | P49841 | 2/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4717958 | 1.00 | KDM4E (0.57) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| SCHEMBL31475494 | 0.89 | KDM4E (0.51) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL31406960 | 0.88 | KDM4E (0.50) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| SCHEMBL4713048 | 0.86 | KDM4E (0.52) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| SCHEMBL4713047 | 0.86 | KDM4E (0.52) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| SCHEMBL4714916 | 0.86 | KDM4E (0.52) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| SCHEMBL28411458 | 0.86 | TOP2A (0.58) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| SCHEMBL13823486 | 0.85 | KCNH2 (0.48) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL13823485 | 0.85 | KCNH2 (0.47) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 | |
| SCHEMBL4713233 | 0.84 | KDM4E (0.60) | KDM4ESMN1; SMN2CYP1A2KCNH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11261205-B2 | Oxazolidinone-quinolone hybrid antibacterial for the parenteral treatment of prophylaxis of bacterial diseases | MORPHOCHEM GMBH (DE) | 2022-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11261205-B2 | Oxazolidinone-quinolone hybrid antibacterial for the parenteral treatment of prophylaxis of bacterial diseases | NQO2, QARS1, RECQL | KDM4E 4487/4885SMN1; SMN2 1257/4885CYP1A2 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.