SCHEMBL29435385

SCHEMBL29435385

CC12CC3(C)CC(C)(C1)CC(c1cc(F)cc(-c4ccccc4-c4cccc(-c5ccccc5-c5cc(F)cc(C67CC8(C)CC(C)(CC(C)(C8)C6)C7)c5O)n4)c1O)(C2)C3

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RARG P13631 1/20 0.32
PDK2 Q15119 2/20 0.30
RARA P10276 1/20 0.30
RARB P10826 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22321079 1.00 RARG (0.32) RARGPDK2RARARARB
SCHEMBL22351761 0.92
SCHEMBL23754713 0.86 RARG (0.34) RARGPDK2RARARARB
SCHEMBL30619637 0.86 RARG (0.34) RARGPDK2RARARARB
SCHEMBL29435400 0.82
SCHEMBL22351760 0.81
SCHEMBL29198842 0.79 BACE1 (0.34) RARGRARB
SCHEMBL23775091 0.78 RARG (0.32) RARG
SCHEMBL22321071 0.77 PTPN11 (0.34) PDK2
SCHEMBL29435398 0.77 PTPN11 (0.34) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113614123-B Transition metal bis (phenoxide) complexes and their use as olefin polymerization catalysts 埃克森美孚化学专利公司 2024-01-23 CN disclosed
US-11254763-B2 Transition metal bis(phenolate) complexes and their use as catalysts for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-02-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11254763-B2 Transition metal bis(phenolate) complexes and their use as catalysts for olefin polymerization CCNT1, CCNA1, CCNE2 RARG 2159/4885PDK2 2700/4885RARA 1611/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.