SCHEMBL2943549

SCHEMBL2943549

Fc1cc(F)c(F)c(-c2c3ccccc3c(-c3c(F)c(F)c(C(F)(F)F)c(F)c3F)c3ccccc23)c1F

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2709796 0.95 MEN1 (0.35) MEN1KMT2A
SCHEMBL2728669 0.91 MEN1 (0.33) MEN1KMT2AALDH1A1KDM4EGAA
SCHEMBL2710306 0.90 MEN1 (0.42) MEN1KMT2AALDH1A1NPSR1KDM4E
SCHEMBL2724744 0.90 MEN1 (0.35) MEN1KMT2AALDH1A1NPSR1NPC1
SCHEMBL2725695 0.90 MEN1 (0.38) MEN1KMT2A
SCHEMBL2709631 0.89 MEN1 (0.35) MEN1KMT2AALDH1A1
SCHEMBL2712747 0.89 MEN1 (0.38) MEN1KMT2AALDH1A1NPSR1NPC1
SCHEMBL2712156 0.88 MEN1 (0.41) MEN1KMT2AALDH1A1NPSR1KDM4E
SCHEMBL2712821 0.88 MEN1 (0.35) MEN1KMT2A
SCHEMBL2712696 0.87 MEN1 (0.37) MEN1KMT2AALDH1A1NPSR1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2445987-B1 BLUE/VIOLET DIPHENYLANTHRACENE CHEMILUMINESCENT FLUORESCERS CYALUME TECH INC (US) 2018-05-02 EP disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
US-8257620-B2 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. (US) 2012-09-04 US disclosed
CN-102482573-A Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES INC 2012-05-30 CN disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYALUME TECHNOLOGIES, INC. 2010-12-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100327240-A1 Blue/violet diphenylanthracene chemiluminescent fluorescers CYP2F1, FLAD1, AFF1 MEN1 1898/4885KMT2A 3905/4885ALDH1A1 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.