Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 1.00 |
| ▸ | RORC | P51449 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | PKM | P14618 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | CASP1 | P29466 | 2/20 | 0.69 |
| ▸ | CASP7 | P55210 | 2/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19764638 | 1.00 | BRD4 (1.00) | BRD4RORCALDH1A1KMT2APKM | |
| SCHEMBL17992507 | 0.93 | BRD4 (1.00) | BRD4RORCALDH1A1KMT2APKM | |
| SCHEMBL17992522 | 0.92 | BRD4 (1.00) | BRD4RORCALDH1A1KMT2APKM | |
| SCHEMBL17992517 | 0.92 | BRD4 (0.87) | BRD4RORCALDH1A1KMT2APKM | |
| SCHEMBL29437335 | 0.92 | BRD4 (0.87) | BRD4RORCALDH1A1KMT2APKM | |
| SCHEMBL29437267 | 0.91 | BRD4 (0.98) | BRD4RORCALDH1A1KMT2APKM | |
| SCHEMBL17992516 | 0.91 | BRD4 (0.98) | BRD4RORCALDH1A1KMT2APKM | |
| SCHEMBL17992497 | 0.90 | BRD4 (1.00) | BRD4ALDH1A1KMT2APKMSMN1; SMN2 | |
| SCHEMBL19764634 | 0.90 | BRD4 (0.81) | BRD4RORCALDH1A1KMT2APKM | |
| SCHEMBL16866198 | 0.90 | BRD4 (0.81) | BRD4RORCALDH1A1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111662226-B | 2-oxo-1, 2-dihydrobenzo [ cd ] indole compound | 中国科学院广州生物医药与健康研究院 | 2022-03-18 | — | — | CN | disclosed |