Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.50 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | BCR | P11274 | 1/20 | 0.36 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 4/20 | 0.33 |
| ▸ | KDR | P35968 | 4/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722846 | 1.00 | STK17B (0.50) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL2722934 | 0.91 | STK17B (0.47) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL18495142 | 0.91 | STK17B (0.47) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL20584280 | 0.91 | STK17B (0.47) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL2722937 | 0.91 | STK17B (0.47) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL15724548 | 0.89 | STK17B (0.52) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL18493721 | 0.88 | STK17B (0.51) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL2724806 | 0.88 | STK17B (0.51) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL2724800 | 0.88 | STK17B (0.51) | STK17BSTK17ATRPA1ABL1BCR | |
| SCHEMBL2722858 | 0.85 | STK17B (0.51) | STK17BSTK17APCSK9IGF1RAAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108283644-B | Transient protection of normal cells during chemotherapy | G1治疗公司 | 2022-03-18 | — | — | CN | disclosed |