Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK17B | O94768 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.33 |
| ▸ | SYK | P43405 | 3/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.30 |
| ▸ | BACE1 | P56817 | 2/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15249218 | 1.00 | STK17B (0.43) | STK17BSTK17ABRD4AAK1SYK | |
| SCHEMBL2722821 | 1.00 | STK17B (0.43) | STK17BSTK17ABRD4AAK1SYK | |
| SCHEMBL15724549 | 0.89 | STK17B (0.44) | STK17BSTK17ABRD4AAK1SYK | |
| SCHEMBL17595889 | 0.88 | STK17B (0.31) | STK17BSTK17A | |
| SCHEMBL18495143 | 0.87 | STK17B (0.43) | STK17BSTK17ABRD4AAK1SYK | |
| SCHEMBL2723400 | 0.87 | STK17B (0.43) | STK17BSTK17ABRD4AAK1SYK | |
| SCHEMBL15238242 | 0.87 | STK17B (0.43) | STK17BSTK17ABRD4AAK1SYK | |
| SCHEMBL2726114 | 0.86 | STK17B (0.41) | STK17BSTK17AAAK1SYKCTSS | |
| SCHEMBL20512302 | 0.86 | STK17B (0.41) | STK17BSTK17AAAK1SYKCTSS | |
| SCHEMBL15238303 | 0.86 | STK17B (0.41) | STK17BSTK17AAAK1SYKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108283644-B | Transient protection of normal cells during chemotherapy | G1治疗公司 | 2022-03-18 | — | — | CN | disclosed |