Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.71 |
| ▸ | AHR | P35869 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.51 |
| ▸ | CLK2 | P49760 | 2/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.51 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.49 |
| ▸ | AURKA | O14965 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29438428 | 0.85 | GAA (0.69) | GAAAHRHSD17B10NPC1RAB9A | |
| SCHEMBL23853488 | 0.83 | GAA (1.00) | GAAAHRHSD17B10TSHRLCK | |
| SCHEMBL29438459 | 0.83 | GAA (1.00) | GAAAHRHSD17B10TSHRLCK | |
| SCHEMBL29438417 | 0.83 | CDK2 (0.65) | GAAAHRHSD17B10NPC1RAB9A | |
| SCHEMBL3421414 | 0.83 | HSD17B10 (0.65) | GAAAHRHSD17B10NPC1RAB9A | |
| SCHEMBL29438436 | 0.82 | GAA (0.62) | GAAAHRHSD17B10NPC1RAB9A | |
| SCHEMBL29438443 | 0.82 | GAA (0.55) | GAAAHRHSD17B10NPC1RAB9A | |
| SCHEMBL10925145 | 0.80 | NPC1 (0.54) | GAAAHRHSD17B10NPC1RAB9A | |
| SCHEMBL29438444 | 0.78 | GAA (0.51) | GAAAHRHSD17B10NPC1RAB9A | |
| SCHEMBL23854212 | 0.78 | GAA (0.60) | GAAAHRHSD17B10TSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220064167-A1 | IMIDAZO-PYRAZOLE CARBOXAMIDE DERIVATIVES AS ANTICANCER AGENTS AND THE SYNTHESIS THEREOF | AVIDIN KFT. (HU) | 2022-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064167-A1 | IMIDAZO-PYRAZOLE CARBOXAMIDE DERIVATIVES AS ANTICANCER AGENTS AND THE SYNTHESIS THEREOF | MYD88, MCL1, MYADM | GAA 4744/4885AHR 881/4885HSD17B10 4038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.