SCHEMBL29438477

SCHEMBL29438477

CC(C)(C)OC(=O)[C@H](CS)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 2/20 0.52
TP53 P04637 2/20 0.52
MDM2 Q00987 1/20 0.48
CASP3 P42574 2/20 0.47
KMT2A Q03164 1/20 0.47
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30206979 1.00 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL175956 1.00 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL175955 1.00 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL29793991 0.89 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL29423449 0.89 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL24899366 0.89 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL3309050 0.89 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL2367138 0.89 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL31370735 0.89 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL25253964 0.88 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12441760-B2 Amino diacids containing peptide modifiers CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2025-10-14 US disclosed
US-20240002433-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2024-01-04 US disclosed
US-11634455-B2 Amino diacids containing peptide modifiers CHEMICAL & BIOPHARMACEUTICAL LABORATORIES OF PATRAS S.A. (GR) 2023-04-25 US disclosed
CN-110003055-B Amino diacids containing peptide modifiers 佩特雷化学和生物制药学实验室有限公司 2022-08-12 CN disclosed
WO-2022037469-A1 LONG-ACTING RELAXIN-2 ANALOG 成都奥达生物科技有限公司 2022-02-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12441760-B2 Amino diacids containing peptide modifiers PTMS, PEPD, NGLY1 MDM4 930/4885TP53 1067/4885MDM2 1037/4885
US-11634455-B2 Amino diacids containing peptide modifiers PTMS, PEPD, VIP MDM4 981/4885TP53 1184/4885MDM2 1136/4885
US-20240002433-A1 AMINO DIACIDS CONTAINING PEPTIDE MODIFIERS PTMS, PEPD, NGLY1 MDM4 930/4885TP53 1067/4885MDM2 1037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.