Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 10/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.64 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.64 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.64 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 2/20 | 0.48 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | P2RY10 | O00398 | 3/20 | 0.47 |
| ▸ | GPR174 | Q9BXC1 | 3/20 | 0.47 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.47 |
| ▸ | SELP | P16109 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9905960 | 1.00 | LPAR1 (0.64) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL9905935 | 0.92 | LPAR1 (0.72) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL31442359 | 0.91 | LPAR1 (0.78) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL6340011 | 0.90 | LPAR1 (0.80) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL13409099 | 0.90 | LPAR1 (0.80) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL29438562 | 0.90 | LPAR1 (0.80) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL9905951 | 0.90 | LPAR1 (0.80) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL6345706 | 0.90 | LPAR1 (0.80) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL6346455 | 0.90 | LPAR1 (0.80) | LPAR1ENPP2LPAR4LPAR5LPAR2 | |
| SCHEMBL29438566 | 0.90 | LPAR1 (0.80) | LPAR1ENPP2LPAR4LPAR5LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230305027-A1 | METHODS FOR TREATING EXACERBATIONS OF INFLAMMATORY RESPIRATORY DISEASES | GENENTECH INC (US) | 2023-09-28 | — | — | US | disclosed |
| EP-4189400-A2 | METHODS FOR TREATING EXACERBATIONS OF INFLAMMATORY RESPIRATORY DISEASES | GENENTECH, INC. (US) | 2023-06-07 | — | — | EP | disclosed |
| CN-116157688-A | Methods for treating exacerbations of inflammatory respiratory diseases | 基因泰克公司 | 2023-05-23 | — | — | CN | disclosed |
| WO-2022026922-A2 | METHODS FOR TREATING EXACERBATIONS OF INFLAMMATORY RESPIRATORY DISEASES | GENENTECH, INC. (US) | 2022-02-03 | — | — | WO | disclosed |