Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEAD1 | P28347 | 3/20 | 0.59 |
| ▸ | YAP1 | P46937 | 1/20 | 0.59 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | IDH2 | P48735 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.37 |
| ▸ | MAP3K12 | Q12852 | 3/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22718083 | 1.00 | TEAD1 (0.59) | TEAD1YAP1SLC6A9IDH2ALDH1A1 | |
| SCHEMBL29438829 | 0.90 | TEAD1 (0.74) | TEAD1YAP1SLC6A9IDH2TLR2 | |
| SCHEMBL22718294 | 0.90 | TEAD1 (0.74) | TEAD1YAP1SLC6A9IDH2TLR2 | |
| SCHEMBL29438926 | 0.88 | TEAD1 (0.59) | TEAD1YAP1SLC6A9TLR2TLR1 | |
| SCHEMBL22718134 | 0.88 | TEAD1 (0.59) | TEAD1YAP1SLC6A9TLR2TLR1 | |
| SCHEMBL22718260 | 0.87 | TEAD1 (0.59) | TEAD1YAP1SLC6A9IDH2ALDH1A1 | |
| SCHEMBL29438857 | 0.87 | TEAD1 (0.59) | TEAD1YAP1SLC6A9IDH2ALDH1A1 | |
| SCHEMBL22718322 | 0.87 | TEAD1 (0.58) | TEAD1YAP1SLC6A9TLR2TLR1 | |
| SCHEMBL22718446 | 0.81 | TEAD1 (0.57) | TEAD1YAP1IDH2TLR2TLR1 | |
| SCHEMBL22843403 | 0.81 | TEAD1 (0.52) | TEAD1YAP1SLC6A9IDH2TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114466839-B | TEAD inhibitors and uses thereof | 医肯纳肿瘤学公司 | 2025-01-07 | — | — | CN | disclosed |
| EP-3976194-A2 | TEAD INHIBITORS AND USES THEREOF | Ikena Oncology, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |