Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.55 |
| ▸ | PKD1 | P98161 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22715280 | 1.00 | MAP3K14 (0.55) | MAP3K14PKD1 | |
| SCHEMBL22715283 | 1.00 | MAP3K14 (0.55) | MAP3K14PKD1 | |
| SCHEMBL22744231 | 1.00 | MAP3K14 (0.55) | MAP3K14PKD1 | |
| SCHEMBL22716281 | 0.95 | MAP3K14 (0.58) | MAP3K14PKD1 | |
| SCHEMBL22716283 | 0.95 | MAP3K14 (0.58) | MAP3K14PKD1 | |
| SCHEMBL22715068 | 0.93 | MAP3K14 (0.56) | MAP3K14PKD1 | |
| SCHEMBL22715064 | 0.93 | MAP3K14 (0.56) | MAP3K14PKD1 | |
| SCHEMBL22744264 | 0.87 | MAP3K14 (0.55) | MAP3K14PKD1 | |
| SCHEMBL22715688 | 0.86 | MAP3K14 (0.55) | MAP3K14PKD1 | |
| SCHEMBL29439443 | 0.86 | MAP3K14 (0.55) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | claimed |
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-118908957-A | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-114222737-B | Small molecule inhibitors of NF- κB induced kinase | 詹森药业有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | disclosed |