Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 8/20 | 0.35 |
| ▸ | JAK1 | P23458 | 8/20 | 0.35 |
| ▸ | JAK3 | P52333 | 8/20 | 0.35 |
| ▸ | LPL | P06858 | 7/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.33 |
| ▸ | TYK2 | P29597 | 4/20 | 0.32 |
| ▸ | STAT3 | P40763 | 4/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL520251 | 0.92 | FFAR1 (0.56) | FFAR1ESR2JAK2JAK1JAK3 | |
| SCHEMBL17247560 | 0.82 | FFAR1 (0.58) | FFAR1LPLLIPG | |
| SCHEMBL2593844 | 0.82 | FFAR1 (0.58) | FFAR1ESR2LPLLIPG | |
| SCHEMBL1854359 | 0.81 | FFAR1 (0.61) | FFAR1JAK2JAK1JAK3LPL | |
| SCHEMBL28398484 | 0.81 | FFAR1 (0.57) | FFAR1LPLLIPG | |
| SCHEMBL23812347 | 0.80 | FFAR1 (0.56) | FFAR1LPLLIPG | |
| SCHEMBL9281960 | 0.80 | FFAR1 (0.59) | FFAR1JAK2JAK1JAK3LPL | |
| SCHEMBL22748460 | 0.80 | FFAR1 (0.56) | FFAR1LPLLIPG | |
| SCHEMBL1331340 | 0.79 | FFAR1 (0.61) | FFAR1LPLLIPG | |
| SCHEMBL9280646 | 0.79 | FFAR1 (0.61) | FFAR1ESR2LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976597-A1 | SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE | Janssen Pharmaceutica NV (BE) | 2022-04-06 | — | — | EP | disclosed |
| CN-114222737-A | Small molecule inhibitor of NF-kB induced kinase | 詹森药业有限公司 | 2022-03-22 | — | — | CN | disclosed |