Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22952600 | 1.00 | KDM4E (0.34) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL28936693 | 1.00 | KDM4E (0.34) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL28711060 | 1.00 | KDM4E (0.34) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL28936695 | 1.00 | KDM4E (0.34) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL22952607 | 1.00 | KDM4E (0.34) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL29440439 | 1.00 | KDM4E (0.34) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL28716084 | 0.88 | DRD1 (0.37) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL22952672 | 0.88 | DRD1 (0.37) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL29440431 | 0.88 | DRD1 (0.37) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 | |
| SCHEMBL28716086 | 0.88 | DRD1 (0.37) | KDM4EMEP1BDRD1SMN1; SMN2KCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4007634-B1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H LUNDBECK AS (DK) | 2024-10-02 | — | — | EP | disclosed |
| CN-114206830-B | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2024-07-30 | — | — | CN | disclosed |
| EP-4007634-A1 | ALCOHOL DERIVATIVES AS KV7 POTASSIUM CHANNEL OPENERS | H. Lundbeck A/S (DK) | 2022-06-08 | — | — | EP | disclosed |
| CN-114206830-A | Alcohol derivatives as Kv7 potassium channel openers | H.隆德贝克有限公司 | 2022-03-18 | — | — | CN | disclosed |