Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.46 |
| ▸ | VIPR2 | P41587 | 6/20 | 0.46 |
| ▸ | PTH1R | Q03431 | 4/20 | 0.45 |
| ▸ | VIPR1 | P32241 | 4/20 | 0.44 |
| ▸ | GLP1R | P43220 | 2/20 | 0.44 |
| ▸ | ECE1 | P42892 | 1/20 | 0.44 |
| ▸ | MUS81 | Q96NY9 | 1/20 | 0.44 |
| ▸ | TFPI | P10646 | 1/20 | 0.43 |
| ▸ | RXFP4 | Q8TDU9 | 1/20 | 0.43 |
| ▸ | RXFP3 | Q9NSD7 | 1/20 | 0.43 |
| ▸ | KRAS | P01116 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31514353 | 0.92 | RXFP1 (0.46) | RXFP1VIPR2PTH1RVIPR1GLP1R | |
| SCHEMBL31670624 | 0.89 | TFPI (0.49) | RXFP1KEAP1PTH1RTFPI | |
| SCHEMBL30905700 | 0.89 | RXFP1 (0.45) | RXFP1KEAP1TFPI | |
| SCHEMBL31670607 | 0.88 | TFPI (0.49) | RXFP1KEAP1VIPR2PTH1RTFPI | |
| SCHEMBL26886898 | 0.88 | NPY4R (0.46) | KEAP1 | |
| SCHEMBL29531521 | 0.86 | TFPI (0.45) | RXFP1KEAP1TFPI | |
| SCHEMBL29677427 | 0.86 | RXFP1 (0.53) | RXFP1VIPR2PTH1RVIPR1TFPI | |
| SCHEMBL30905698 | 0.86 | NPY4R (0.47) | KEAP1TFPI | |
| SCHEMBL29470910 | 0.86 | RXFP1 (0.56) | RXFP1VIPR2VIPR1TFPI | |
| SCHEMBL29624007 | 0.85 | VIPR2 (0.52) | RXFP1KEAP1VIPR2PTH1RVIPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096656-A1 | NANOCARRIERS HAVING SURFACE CONJUGATED PEPTIDES AND USES THEREOF FOR SUSTAINED LOCAL RELEASE OF DRUGS | NORTHWESTERN UNIVERSITY | 2022-03-31 | — | — | US | disclosed |