Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 2/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | VCP | P55072 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26346212 | 1.00 | HRH4 (0.49) | HRH4MAPTGFERHRH3SMN1; SMN2 | |
| SCHEMBL29442399 | 0.90 | HRH4 (0.45) | HRH4MAPTGFERHRH3SMN1; SMN2 | |
| SCHEMBL26346218 | 0.90 | HRH4 (0.45) | HRH4MAPTGFERHRH3SMN1; SMN2 | |
| SCHEMBL20681703 | 0.89 | SMN1; SMN2 (0.52) | HRH4MAPTGFERHRH3SMN1; SMN2 | |
| SCHEMBL29442441 | 0.89 | SMN1; SMN2 (0.52) | HRH4MAPTGFERHRH3SMN1; SMN2 | |
| SCHEMBL26346198 | 0.88 | SMN1; SMN2 (0.54) | HRH4MAPTGFERHRH3SMN1; SMN2 | |
| SCHEMBL26346468 | 0.87 | HRH4 (0.53) | HRH4MAPTGFERHRH3POLB | |
| SCHEMBL29442385 | 0.87 | HRH4 (0.46) | HRH4MAPTGFERHRH3SMN1; SMN2 | |
| SCHEMBL26346217 | 0.87 | HRH4 (0.46) | HRH4MAPTGFERHRH3SMN1; SMN2 | |
| SCHEMBL20692326 | 0.86 | HRH4 (0.56) | HRH4MAPTGFERHRH3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022046999-A1 | MODULATORS OF MYB-MEDIATED TRANSCRIPTION AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2022-03-03 | — | — | WO | disclosed |