Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 12/20 | 1.00 |
| ▸ | EGFR | P00533 | 16/20 | 0.88 |
| ▸ | SRC | P12931 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22590126 | 1.00 | ERBB2 (1.00) | ERBB2EGFRSRC | |
| SCHEMBL29444165 | 1.00 | ERBB2 (1.00) | ERBB2EGFRSRC | |
| SCHEMBL29752032 | 0.94 | EGFR (1.00) | ERBB2EGFR | |
| SCHEMBL22598672 | 0.94 | EGFR (1.00) | ERBB2EGFR | |
| SCHEMBL22598775 | 0.93 | ERBB2 (0.87) | ERBB2EGFRSRC | |
| SCHEMBL29752078 | 0.93 | ERBB2 (0.87) | ERBB2EGFRSRC | |
| SCHEMBL22598674 | 0.92 | EGFR (1.00) | ERBB2EGFRSRC | |
| SCHEMBL29751985 | 0.92 | EGFR (1.00) | ERBB2EGFRSRC | |
| SCHEMBL22590135 | 0.92 | ERBB2 (0.84) | ERBB2EGFRSRC | |
| SCHEMBL22598685 | 0.91 | EGFR (1.00) | ERBB2EGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118852118-A | Compounds that inhibit tyrosine kinase activity and pharmaceutical compositions comprising the same | 德州大学系统董事会 | 2024-10-29 | — | — | CN | disclosed |
| CN-114026083-B | Heterocyclic inhibitors of tyrosine kinases | 德州大学系统董事会 | 2024-07-09 | — | — | CN | disclosed |
| EP-3962908-A1 | HETEROCYCLIC INHIBITORS OF TYROSINE KINASE | Board of Regents, The University of Texas System (US) | 2022-03-09 | — | — | EP | disclosed |
| CN-114026083-A | Heterocyclic inhibitors of tyrosine kinases | 德州大学系统董事会 | 2022-02-08 | — | — | CN | disclosed |