Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 3/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL966421 | 1.00 | TYMS (0.57) | TYMSTHRBTHRATOP1MAPT | |
| SCHEMBL27947898 | 0.82 | TYMS (0.39) | TYMSTOP1MAPTHPGDALDH1A1 | |
| SCHEMBL27947897 | 0.81 | TYMS (0.50) | TYMSTHRBTHRANPC1RAB9A | |
| SCHEMBL28729483 | 0.79 | TYMS (0.47) | TYMSTHRBTHRATOP1MAPT | |
| SCHEMBL2176042 | 0.79 | KDM4E (0.50) | TYMSMAPTHPGDALDH1A1MEN1 | |
| SCHEMBL28406639 | 0.79 | TYMS (0.47) | TYMSTHRBTHRATOP1MAPT | |
| SCHEMBL13899925 | 0.78 | TYMS (0.52) | TYMSTHRBTHRAMAPTHPGD | |
| SCHEMBL9320071 | 0.78 | TTR (0.49) | TYMSTHRBTHRAMAPTHPGD | |
| SCHEMBL28707279 | 0.78 | TYMS (0.47) | TYMSTHRBTHRAMAPTHPGD | |
| SCHEMBL11908091 | 0.78 | ELANE (0.39) | TYMSTOP1MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279731-B2 | Ligand functional substrates | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279731-B2 | Ligand functional substrates | PCNA, POLM, POLL | TYMS 1374/4885THRB 3995/4885THRA 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.