Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 20/20 | 1.00 |
| ▸ | PDE8A | O60658 | 3/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6911014 | 1.00 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL17545207 | 1.00 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6909572 | 0.87 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6910585 | 0.87 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6910604 | 0.85 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6910452 | 0.83 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6909245 | 0.83 | PDE8B (1.00) | PDE8BPDE8A | |
| SCHEMBL6911266 | 0.82 | PDE8B (0.72) | PDE8BPDE8A | |
| SCHEMBL6910356 | 0.80 | PDE8B (0.71) | PDE8BPDE8A | |
| SCHEMBL6910855 | 0.79 | PDE8B (0.68) | PDE8BPDE8A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026098636-A1 | USE OF PDE4 INHIBITOR FOR TREATING AND/OR PREVENTING PULMONARY DISEASES | 正大制药(广州)有限公司 | 2026-05-15 | — | — | WO | disclosed |
| EP-3894011-B1 | MEMBRANE BOUND IL12 COMPOSITIONS AND METHODS FOR TUNABLE REGULATION | OBSIDIAN THERAPEUTICS INC (US) | 2025-09-17 | — | — | EP | disclosed |
| EP-3806888-B1 | PDE5 DERIVED REGULATORY CONSTRUCTS AND METHODS OF USE IN IMMUNOTHERAPY | OBSIDIAN THERAPEUTICS INC (US) | 2024-01-31 | — | — | EP | disclosed |
| US-11666642-B2 | PDE5 compositions and methods for immunotherapy | OBSIDIAN THERAPEUTICS, INC. (US) | 2023-06-06 | — | — | US | disclosed |
| US-20230074330-A1 | PDE5 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY | OBSIDIAN THERAPEUTICS, INC. (US) | 2023-03-09 | — | — | US | disclosed |
| US-20220403001-A1 | PDE5 DERIVED REGULATORY CONSTRUCTS AND METHODS OF USE IN IMMUNOTHERAPY | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | US | disclosed |
| US-20220056092-A1 | MEMBRANE BOUND IL12 COMPOSITIONS AND METHODS FOR TUNABLE REGULATION | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-02-24 | — | — | US | disclosed |
| US-11241485-B2 | PDE5 compositions and methods for immunotherapy | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-02-08 | — | — | US | disclosed |