Triphenylmethanol

Triphenylmethanol

SCHEMBL29446231

OC(c1ccccc1)(c1ccccc1)c1ccccc1.[Sn]

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 5/20 0.48
CYP1A2 P05177 3/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
ALDH1A1 P00352 3/20 0.45
TSHR P16473 2/20 0.45
KCNN4 O15554 1/20 0.45
CYP2D6 P10635 1/20 0.45
HPGD P15428 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
CFTR P13569 1/20 0.43
GOPC Q9HD26 1/20 0.43
KMT2A Q03164 1/20 0.43
CRHBP P24387 1/20 0.42
CRHR2 Q13324 1/20 0.42
SLC2A1 P11166 1/20 0.42
ALOX15 P16050 1/20 0.42
ESR1 P03372 2/20 0.40
ESR2 Q92731 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triphenylmethanol SCHEMBL700 0.97 CYP19A1 (0.50) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
Triphenylmethanol SCHEMBL1332873 0.97 CYP19A1 (0.50) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
Triphenylmethanol SCHEMBL456603 0.97 CYP19A1 (0.50) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
Triphenylmethanol SCHEMBL1101236 0.93 CYP1A2 (0.50) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL9050608 0.93 CYP19A1 (0.54) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
Triphenylmethanol SCHEMBL1565321 0.93 CYP19A1 (0.48) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
Triphenylmethanol SCHEMBL6057181 0.90 CYP19A1 (0.48) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
Triphenylmethanol SCHEMBL28378880 0.90 CYP1A2 (0.48) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
Triphenylmethanol SCHEMBL19583303 0.88 CYP1A2 (0.47) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1
SCHEMBL21842336 0.85 CYP2C9 (0.54) CYP19A1CYP1A2CYP2C9CYP2C19ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11242421-B2 Highly branched, low molecular weight polyolefins and methods for their production NORTHWESTERN UNIVERSITY (US) 2022-02-08 US disclosed