Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.70 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.70 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.70 |
| ▸ | ECE1 | P42892 | 1/20 | 0.61 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.50 |
| ▸ | PADI1 | Q9ULC6 | 1/20 | 0.50 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.50 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.50 |
| ▸ | PADI2 | Q9Y2J8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GNE | Q9Y223 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.45 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23069157 | 1.00 | KDM4E (0.70) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL29355234 | 0.98 | KDM4E (0.73) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL143651 | 0.98 | KDM4E (0.73) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL70765 | 0.95 | KDM4E (0.76) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL29357675 | 0.95 | KDM4E (0.76) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL3753307 | 0.90 | KDM4E (0.61) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL1456359 | 0.87 | KDM4E (0.64) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL29094219 | 0.85 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| Dipicolinic Acid SCHEMBL29094220 | 0.85 | KDM4E (0.94) | KDM4EALOX15TSHRACMSDTDP1 | |
| SCHEMBL15452283 | 0.84 | KDM4E (0.59) | KDM4EALOX15TSHRACMSDTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12180295-B2 | Humanized anti-SIRPα antibodies | BYONDIS B.V. (NL) | 2024-12-31 | — | — | US | disclosed |
| EP-4400173-A2 | ANTI-SIRP ALPHA ANTIBODIES | Byondis B.V. (NL) | 2024-07-17 | — | — | EP | disclosed |
| CN-118271443-A | Anti-SIRP alpha antibodies | 拜奥迪斯私人有限公司 | 2024-07-02 | — | — | CN | disclosed |
| EP-3625259-B1 | ANTI-SIRPALPHA ANTIBODIES | BYONDIS BV (NL) | 2024-04-17 | — | — | EP | disclosed |
| US-11718681-B2 | Anti-SIRP α antibodies | BYONDIS B.V. (NL) | 2023-08-08 | — | — | US | disclosed |
| US-20220195063-A1 | ANTI-SIRP ALPHA ANTIBODIES | BYONDIS BV (NL) | 2022-06-23 | — | — | US | disclosed |
| US-11274159-B2 | Anti-SIRPα antibodies | BYONDIS B.V. (NL) | 2022-03-15 | — | — | US | disclosed |