Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19627656 | 1.00 | SCN8A (0.64) | SCN8ASCN1A | |
| SCHEMBL29447358 | 0.93 | SCN8A (0.66) | SCN8ASCN1A | |
| SCHEMBL19614328 | 0.92 | SCN8A (0.59) | SCN8ASCN1A | |
| SCHEMBL19614326 | 0.92 | SCN8A (0.59) | SCN8ASCN1A | |
| SCHEMBL19613746 | 0.85 | SCN8A (0.70) | SCN8ASCN1A | |
| SCHEMBL19613744 | 0.85 | SCN8A (0.70) | SCN8ASCN1A | |
| SCHEMBL19627651 | 0.84 | SCN8A (0.63) | SCN8ASCN1A | |
| SCHEMBL29447392 | 0.84 | SCN8A (0.63) | SCN8ASCN1A | |
| SCHEMBL19627702 | 0.83 | SCN8A (0.65) | SCN8ASCN1A | |
| SCHEMBL29447375 | 0.83 | SCN8A (0.65) | SCN8ASCN1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11299490-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2022-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11299490-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | SCN1A, SCN1B, SCN2B | SCN8A 14/4885SCN1A 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.