Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN8A | Q9UQD0 | 15/20 | 0.43 |
| ▸ | SCN1A | P35498 | 11/20 | 0.43 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19613807 | 1.00 | SCN8A (0.43) | SCN8ASCN1ASTSEPHX2MAPT | |
| SCHEMBL19613809 | 1.00 | SCN8A (0.43) | SCN8ASCN1ASTSEPHX2MAPT | |
| SCHEMBL19627748 | 0.94 | SCN8A (0.43) | SCN8ASCN1AMEN1KMT2A | |
| SCHEMBL19614254 | 0.92 | SCN8A (0.46) | SCN8ASCN1ARORC | |
| SCHEMBL19614252 | 0.92 | SCN8A (0.46) | SCN8ASCN1ARORC | |
| SCHEMBL19628753 | 0.91 | SCN8A (0.41) | SCN8ASCN1ASTSEPHX2MAPT | |
| SCHEMBL29447384 | 0.91 | SCN8A (0.41) | SCN8ASCN1ASTSEPHX2MAPT | |
| SCHEMBL28521482 | 0.91 | SCN8A (0.41) | SCN8ASCN1ASTSEPHX2MAPT | |
| SCHEMBL28519887 | 0.86 | STS (0.41) | STSEPHX2MAPTMEN1KMT2A | |
| SCHEMBL29447360 | 0.86 | STS (0.41) | STSEPHX2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11299490-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | XENON PHARMACEUTICALS INC. (CA) | 2022-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11299490-B2 | Benzenesulfonamide compounds and their use as therapeutic agents | SCN1A, SCN1B, SCN2B | SCN8A 14/4885SCN1A 1/4885STS 181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.