Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.92 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19233439 | 1.00 | KDR (0.92) | KDR | |
| SCHEMBL29448675 | 0.96 | KDR (1.00) | KDR | |
| SCHEMBL19233301 | 0.96 | KDR (1.00) | KDR | |
| SCHEMBL29448702 | 0.94 | KDR (1.00) | KDR | |
| SCHEMBL19233420 | 0.94 | KDR (1.00) | KDR | |
| SCHEMBL19233403 | 0.88 | KDR (0.80) | KDR | |
| SCHEMBL29448695 | 0.88 | KDR (0.80) | KDR | |
| SCHEMBL20577719 | 0.87 | KDR (0.88) | KDR | |
| SCHEMBL29448689 | 0.87 | KDR (0.77) | KDR | |
| SCHEMBL19233581 | 0.87 | KDR (0.77) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3412670-B1 | PYRIDINE DERIVATIVES INHIBITING RAF KINASE AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USE THEREOF | SAMJIN PHARM CO LTD (KR) | 2022-03-09 | — | — | EP | claimed |
| EP-3412670-B1 | PYRIDINE DERIVATIVES INHIBITING RAF KINASE AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USE THEREOF | SAMJIN PHARM CO LTD (KR) | 2022-03-09 | — | — | EP | disclosed |