Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19233284 | 1.00 | KDR (1.00) | KDR | |
| SCHEMBL19233431 | 0.91 | KDR (0.84) | KDR | |
| SCHEMBL19233290 | 0.91 | KDR (0.83) | KDR | |
| SCHEMBL19233296 | 0.90 | KDR (1.00) | KDR | |
| SCHEMBL20577886 | 0.89 | KDR (0.83) | KDR | |
| SCHEMBL19233589 | 0.85 | KDR (0.77) | KDR | |
| SCHEMBL19233588 | 0.84 | KDR (0.89) | KDR | |
| SCHEMBL19233295 | 0.82 | KDR (0.80) | KDR | |
| SCHEMBL19233299 | 0.81 | KDR (1.00) | KDR | |
| SCHEMBL19233237 | 0.80 | KDR (0.81) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3412670-B1 | PYRIDINE DERIVATIVES INHIBITING RAF KINASE AND VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR, PHARMACEUTICAL COMPOSITION CONTAINING THEM AND USE THEREOF | SAMJIN PHARM CO LTD (KR) | 2022-03-09 | — | — | EP | disclosed |