Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 11/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 8/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | SNCA | P37840 | 3/20 | 0.39 |
| ▸ | CYBB | P04839 | 2/20 | 0.39 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.39 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22960484 | 1.00 | NOX1 (0.53) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960525 | 0.83 | NOX1 (0.58) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960444 | 0.81 | NOX1 (0.55) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960469 | 0.81 | NOX1 (0.54) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960592 | 0.78 | NOX1 (0.51) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960576 | 0.77 | NOX1 (0.70) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960609 | 0.77 | NOX1 (0.62) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960522 | 0.77 | NOX1 (0.55) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960495 | 0.76 | NOX1 (0.68) | NOX1KCNH2GAAMAPTMEN1 | |
| SCHEMBL22960499 | 0.76 | NOX1 (0.60) | NOX1KCNH2GAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181170-B | 10H-phenothiazine iron death inhibitor and preparation method and application thereof | 成都恒昊创新科技有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-114181170-A | 10H-phenothiazine iron death inhibitor and preparation method and application thereof | 成都恒昊创新科技有限公司 | 2022-03-15 | — | — | CN | disclosed |