SCHEMBL29449497

SCHEMBL29449497

N=C(N)NCCC[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CC(=O)O)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NPY4R P50391 18/20 0.62
▸ NPY1R P25929 11/20 0.62
▸ NPY5R Q15761 9/20 0.62
▸ NPY2R P49146 7/20 0.62
▸ VIPR1 P32241 1/20 0.49
▸ VIPR2 P41587 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31280255 0.95 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31279260 0.95 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL31280076 0.95 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30153268 0.94 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29540161 0.93 NPY4R (0.66) NPY4RNPY1RNPY5RNPY2R
SCHEMBL27549042 0.93 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL27549044 0.93 NPY4R (0.65) NPY4RNPY1RNPY5RNPY2R
SCHEMBL29611536 0.92 NPY4R (0.58) NPY4RNPY1RNPY5RNPY2RVIPR1
Selcopintide SCHEMBL30691875 0.92 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R
Selcopintide SCHEMBL30691874 0.92 NPY4R (0.62) NPY4RNPY1RNPY5RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023020290-A1 POLYPEPTIDE DERIVED FROM DRY-CURED HAM AND CAPABLE OF ALLEVATING ALCOHOLIC LIVER DAMAGE, AND PREPARATION METHOD THEREFOR 合肥工业大学 2023-02-23 — — WO claimed
CN-113480608-B Dry-pickled ham-derived polypeptide capable of relieving alcoholic liver injury and preparation method thereof 合肥工业大学 2022-09-02 — — CN claimed
CN-114304354-A Tabletting candy rich in dry-cured ham active peptide and functional lipid and preparation method thereof 合肥工业大学 2022-04-12 — — CN claimed
WO-2023020290-A1 POLYPEPTIDE DERIVED FROM DRY-CURED HAM AND CAPABLE OF ALLEVATING ALCOHOLIC LIVER DAMAGE, AND PREPARATION METHOD THEREFOR 合肥工业大学 2023-02-23 — — WO disclosed
WO-2023020290-A1 POLYPEPTIDE DERIVED FROM DRY-CURED HAM AND CAPABLE OF ALLEVATING ALCOHOLIC LIVER DAMAGE, AND PREPARATION METHOD THEREFOR 合肥工业大学 2023-02-23 — — WO disclosed
CN-113480608-B Dry-pickled ham-derived polypeptide capable of relieving alcoholic liver injury and preparation method thereof 合肥工业大学 2022-09-02 — — CN disclosed
CN-113480608-B Dry-pickled ham-derived polypeptide capable of relieving alcoholic liver injury and preparation method thereof 合肥工业大学 2022-09-02 — — CN disclosed
CN-114304354-A Tabletting candy rich in dry-cured ham active peptide and functional lipid and preparation method thereof 合肥工业大学 2022-04-12 — — CN disclosed
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