SCHEMBL29449507

SCHEMBL29449507

Cc1c(F)ccc(OS(C)(=O)=O)c1C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.47
KDM4E B2RXH2 1/20 0.47
CYP1A2 P05177 2/20 0.40
HSD17B10 Q99714 2/20 0.40
ALPL P05186 1/20 0.40
TSHR P16473 1/20 0.40
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
SLC22A12 Q96S37 2/20 0.36
ALDH1A1 P00352 3/20 0.34
MEN1 O00255 1/20 0.34
GLA P06280 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
PKM P14618 1/20 0.34
CYP2C19 P33261 1/20 0.34
RECQL P46063 1/20 0.34
PDE4B Q07343 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20582877 1.00 KMT2A (0.47) KMT2AKDM4ECYP1A2HSD17B10ALPL
SCHEMBL20582860 0.87 KDM4E (0.56) KMT2AKDM4ECYP1A2HSD17B10ALPL
SCHEMBL29497737 0.87 KDM4E (0.56) KMT2AKDM4ECYP1A2HSD17B10ALPL
SCHEMBL3748501 0.78 KDM4E (0.38) KMT2AKDM4ECYP1A2HSD17B10ALPL
Hydrogen Sulfide SCHEMBL6129793 0.78 KDM4E (0.49) KMT2AKDM4ECYP1A2HSD17B10ALPL
SCHEMBL20582874 0.77 KMT2A (0.45) KMT2AKDM4ECYP1A2HSD17B10ALPL
SCHEMBL29497713 0.77 KMT2A (0.45) KMT2AKDM4ECYP1A2HSD17B10ALPL
SCHEMBL20582859 0.76 KDM4E (0.47) KMT2AKDM4ECYP1A2HSD17B10ALPL
SCHEMBL20582983 0.76 KMT2A (0.47) KMT2AKDM4ECYP1A2HSD17B10ALPL
SCHEMBL20583011 0.76 KDM4E (0.47) KMT2AKDM4ECYP1A2HSD17B10ALPL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114702411-A Method for producing 1, 2-benzenedimethanol compound 高文作物保护公司 2022-07-05 CN disclosed
CN-108602765-B Method for producing 1, 2-benzenedimethanol compound 高文有限公司 2022-05-03 CN disclosed
CN-110776441-B Synthesis method of 4-fluoro-2, 3-dimethylphenylmethylsulfonate 西安淳甄新材料有限公司 2022-03-22 CN disclosed
CN-110776441-B Synthesis method of 4-fluoro-2, 3-dimethylphenylmethylsulfonate 西安淳甄新材料有限公司 2022-03-22 CN disclosed