Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE8B | O95263 | 1/20 | 0.35 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 4/20 | 0.33 |
| ▸ | MTOR | P42345 | 4/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953130 | 0.85 | KDM4E (0.33) | PDE8BTDP2PDE10A | |
| SCHEMBL30784984 | 0.69 | PIK3CA (0.39) | PDE8BTDP2PIK3CAMTORPDE10A | |
| SCHEMBL14833240 | 0.67 | GAA (0.44) | PDE8BTDP2PIK3CAMTOR | |
| SCHEMBL20692987 | 0.61 | PDE10A (0.40) | PDE8BTDP2PIK3CAMTORPDE10A | |
| SCHEMBL1694217 | 0.61 | PIK3CA (0.40) | PDE8BPIK3CAMTOR | |
| SCHEMBL2953112 | 0.60 | MTOR (0.34) | PIK3CAMTOR | |
| SCHEMBL26975235 | 0.59 | PIK3CA (0.39) | PDE8BTDP2PIK3CAMTORPDE10A | |
| SCHEMBL28004912 | 0.59 | PNP (0.42) | PDE10A | |
| SCHEMBL29763294 | 0.59 | PIK3CA (0.33) | PDE8BPIK3CAMTOR | |
| SCHEMBL855517 | 0.59 | PIK3CA (0.38) | TDP2PIK3CAMTORPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010111406-A2 | COMPOUNDS AND THERAPEUTIC USES THEREOF | MYRIAD PHARMACEUTICALS, INC. (US) | 2010-09-30 | — | — | WO | claimed |