Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21226340 | 1.00 | KMT2A (0.60) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL21217944 | 0.89 | KMT2A (0.56) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL24621432 | 0.87 | KMT2A (0.51) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL24349368 | 0.87 | KMT2A (0.51) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL24349371 | 0.86 | KMT2A (0.49) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL19008424 | 0.82 | KMT2A (0.47) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL24621431 | 0.81 | KMT2A (0.46) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL21217552 | 0.81 | KMT2A (0.54) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL16134262 | 0.79 | KMT2A (0.44) | KMT2AMBNL1NPC1RAB9AALDH1A1 | |
| SCHEMBL24349328 | 0.79 | KMT2A (0.46) | KMT2AMBNL1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114031606-B | Indenoquinoline compound and preparation method and application thereof | 广东聚华印刷显示技术有限公司 | 2023-01-24 | — | — | CN | disclosed |
| CN-114031606-A | Indenoquinoline compound and preparation method and application thereof | 广东聚华印刷显示技术有限公司 | 2022-02-11 | — | — | CN | disclosed |