Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WHR1 | P49842 | 3/20 | 0.70 |
| ▸ | EHMT2 | Q96KQ7 | 9/20 | 0.59 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.59 |
| ▸ | CCR4 | P51679 | 8/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL20602884 | 1.00 | WHR1 (0.70) | WHR1EHMT2EHMT1CCR4 | |
| Trifluoroacetic Acid SCHEMBL22026553 | 1.00 | WHR1 (0.70) | WHR1EHMT2EHMT1CCR4 | |
| Trifluoroacetic Acid SCHEMBL20602889 | 0.92 | EHMT2 (0.62) | WHR1EHMT2EHMT1 | |
| SCHEMBL20620885 | 0.91 | EHMT2 (0.70) | EHMT2EHMT1CCR4 | |
| SCHEMBL20620888 | 0.91 | EHMT2 (0.70) | EHMT2EHMT1CCR4 | |
| SCHEMBL20602893 | 0.91 | EHMT2 (0.70) | EHMT2EHMT1CCR4 | |
| Trifluoroacetic Acid SCHEMBL22026550 | 0.90 | EHMT2 (0.64) | WHR1EHMT2EHMT1 | |
| SCHEMBL20621257 | 0.90 | EHMT2 (0.71) | EHMT2EHMT1CCR4 | |
| SCHEMBL20621255 | 0.90 | EHMT2 (0.71) | EHMT2EHMT1CCR4 | |
| SCHEMBL20620831 | 0.86 | EHMT2 (0.72) | EHMT2EHMT1CCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254654-B2 | Heterochromatin gene repression inhibitors | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2022-02-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11254654-B2 | Heterochromatin gene repression inhibitors | CTCF, EHMT2, CBX3 | WHR1 158/4885EHMT2 2/4885EHMT1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.