Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP46A1 | Q9Y6A2 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22719294 | 1.00 | CYP46A1 (0.47) | CYP46A1ALDH1A1KDM4EPOLBGAA | |
| SCHEMBL22728432 | 0.91 | CYP46A1 (0.39) | CYP46A1ALDH1A1 | |
| SCHEMBL22719256 | 0.91 | CYP46A1 (0.53) | CYP46A1ALDH1A1 | |
| SCHEMBL29453637 | 0.91 | CYP46A1 (0.53) | CYP46A1ALDH1A1 | |
| SCHEMBL22719285 | 0.88 | CYP46A1 (0.50) | CYP46A1ALDH1A1 | |
| SCHEMBL22719463 | 0.86 | CYP46A1 (0.48) | CYP46A1ALDH1A1 | |
| SCHEMBL22719464 | 0.86 | CYP46A1 (0.52) | CYP46A1ALDH1A1KDM4E | |
| SCHEMBL22719283 | 0.86 | CYP46A1 (0.65) | CYP46A1ALDH1A1 | |
| SCHEMBL22719149 | 0.81 | CYP46A1 (0.61) | CYP46A1ALDH1A1POLB | |
| SCHEMBL22719351 | 0.80 | CYP46A1 (0.49) | CYP46A1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3976186-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Sage Therapeutics, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |